Nicola Amoroso

Language of Toxicity: An eXplainable Artificial Intelligence Approach

Abstract Toxicity prediction in small molecules represents a fundamental challenge in drug development and chemical safety assessment. Traditional approaches heavily rely on predefined molecular descriptors or fingerprints, potentially limiting the ability to capture complex and...

Sustained seizure reduction, treatment simplification, and high retention with cenobamate: A 12‐month real‐world study in refractory and ultra‐refractory focal epilepsy

Abstract Objective To assess the 12‐month clinical impact of cenobamate (CNB) in adults with drug‐resistant focal epilepsy in clinical practice, exploring whether outcomes differed according to prior antiseizure medication (ASM) exposure. Methods This single‐center, retrospective...