Nicla Maria La Verde

Changing cancer prognosis among people with HIV over two decades: Trends in mortality and net survival in Milan, Italy

BACKGROUND: Cancer is a major cause of morbidity and mortality among people with HIV (PWH). We assessed temporal trends in five-year mortality and compared recent cancer survival with standardized Italian general-population estimates. METHODS: We conducted a retrospective single-...

The impact of PROgnostic SIgnatures in stage II colon cancer patients enrolled in the phase III clinical trial TOSCA: the PROSIT study

BACKGROUND: Adjuvant chemotherapy (ACT) indication in stage II colorectal cancer (CRC) remains challenging, as clinical, pathological, and ctDNA inadequately predict benefit. Immune infiltration correlates with outcome, yet transcriptional signatures have not been systematically...