Niall M. Corcoran

Integrated signatures define mutational processes in prostate cancer

Prostate cancer follows a long and heterogeneous disease course with incompletely understood aetiology. Here, we dissect the mutational processes shaping the genomes of 959 donors from the Pan Prostate Cancer Group (PPCG) and assess their clinical relevance. By integrating de nov...

Tumour Volume Independently Predicts Metastasis in ISUP 2 Prostate Cancer

Background and Objectives: The outcomes for patients with localised prostate cancer are variable, even within defined tumour grades or clinical risk groups. Identifying features associated with disease aggression is imperative in contemporary PCa research. ISUP 2 PCa is particula...