Nesma Ahmed Shiha

Repositioning pentoxifylline via inhalable novasomes for pulmonary fibrosis: from statistical optimization to in-vivo evaluation

Pulmonary fibrosis (PF) represents the final stage of lung injuries, triggered mainly by viral infections. Pentoxifylline (PTX) is a hemorheologic drug that has been recently repurposed for the prophylaxis of PF. Nevertheless, it exhibits low oral bioavailability. This study aims...