Neerathilingam Nalladhambi

Harnessing Diazo Compounds as Alkoxycarbonyl Methylene Radical Linchpins: Truce–Smiles Rearrangement toward Amido Esters and Isoquinolinedione Scaffolds

Abstract The radical reactivity of acceptor-type diazo compounds is harnessed in the photochemical Truce–Smiles rearrangement of N-aryl-N-arylsulfonyl acrylamides to access β,β′-disubstituted amido esters. The rational design of starting materials and the cascade technique can be...