Nedim Çekmen

Anti-inflammatory and antioxidant effects of dexmedetomidine infusion in rats with mesenteric ischemia-reperfusion injury

Our study aimed to investigate the anti-inflammatory and antioxidant effects of intraperitoneal Dexmedetomidine (DEX) infusion at different doses in rats with mesenteric ischemia-reperfusion (I/R) injury. Forty rats were randomly divided into five groups ( n = 8). I/R was not ind...

Intranasal dexmedetomidine versus intravenous propofol for the prevention of pediatric emergence delirium following general anesthesia: A randomized controlled trial

Emergence agitation (EA) and emergence delirium (ED) are significant postoperative complications in pediatric anesthesia, requiring effective strategies for prevention and management. This study aimed to evaluate the efficacy of intranasal dexmedetomidine, intravenous propofol, a...