Nancy Aguilera

In vivo adaptive optics retinal imaging reveals rod-mediated cone photoreceptor disorganization in RHO-associated retinitis pigmentosa

Abstract Pathogenic variants in the rhodopsin ( RHO ) gene are the most common cause of autosomal dominant retinitis pigmentosa leading to photoreceptor degeneration. Quantitative imaging using adaptive optics (AO) revealed irregularities in cone organization, even in relatively...

Open-Source Software Suite for Cell Detection and Segmentation in Adaptive Optics Retinal Imaging

Purpose: The purpose of this study was to present a suite of open-source software tools for automated and interactive annotation (detection and segmentation) of retinal cells from adaptive optics (AO) images. Methods: Three related software packages were developed, implementing m...