Nabil F. Saba

MUC5B orchestrates tobacco-driven metabolic rewiring and immunosuppression in head and neck squamous cell carcinoma

Abstract Background Tobacco exposure is a major risk factor for HPV-unrelated head and neck squamous cell carcinoma (HNSCC) and is associated with poor clinical outcomes; however, the molecular regulators through which tobacco exposure drives tumor aggressiveness and immunosuppre...