Na Yang

A 6His-2Flag dual-tag strategy enables high-yield production of antimicrobial peptide N6 in Pichia pastoris to combat multidrug-resistant Klebsiella pneumonia

In response to the global threat posed by multidrug-resistant Klebsiella pneumoniae , this study established an efficient heterologous expression system for the antimicrobial peptide N6 in Pichia pastoris X-33. By employing an innovative 6His-2Flag dual-tag fusion strategy couple...

AI-driven discovery of self-assembled antimicrobial peptides with dual antibacterial and wound-healing functions against multidrug-resistant infections

The rapid emergence of multidrug-resistant bacterial infections, particularly those caused by methicillin-resistant Staphylococcus aureus and carbapenem-resistant Acinetobacter baumannii , poses a critical challenge to global healthcare. Antimicrobial peptides (AMPs) are promisin...