Murong Zhou

SVPG: a pangenome-based structural variant detection approach and rapid augmentation of pangenome graphs with new samples

Abstract Breakthrough advances in long-read sequencing have opened unprecedented opportunities to study genetic variations through pangenome analysis, yet tools that effectively leverage such frameworks for structural variant (SV) detection remain limited. In addition, efficient...

NEOGRAN: traceable graph-text fusion for disease–protein relation prediction in biomedical knowledge graphs

Abstract Background Accurately predicting disease–protein relations in biomedical knowledge graphs helps link disease phenotypes to molecular mechanisms and supports disease-related knowledge discovery and candidate target identification. Biomedical knowledge graphs organize mult...