Munishkumar Buch

Improving pharmacokinetics and pharmacodynamics of berberine hydrochloride using solid dispersion: A therapeutic approach to hyperlipidemia

Berberine is an isoquinoline alkaloid that acts as a natural PCSK9 inhibitor. By inhibiting PCSK9, it upregulates Low-Density Lipoprotein (LDL) receptors and helps maintain lipid metabolism. Although it is a promising hypolipidemic agent, its clinical application is limited by po...