Mrs. Jayalakshmi Venugopal*, Dr. M. P. Amshaja, Mr. Mugilan G., Mr. Mohammed Nawaz Abrar P. N., Ms. Monisha J.

CHALLENGES IN USING PHARMACOMETRICS MODEL IN DOSING MERCAPTOPURINES IN LEUKEMIA

Mercaptopurine (6‑MP) is a key component of maintenance therapy for acute lymphoblastic leukemia, but optimizing its dose is challenging due to large differences between patients in how the drug is metabolized and how they respond. This review discusses the pharmacometric models...

CHALLENGES IN USING PHARMACOMETRICS MODEL IN DOSING MERCAPTOPURINES IN LEUKEMIA

Mercaptopurine (6‑MP) is a key component of maintenance therapy for acute lymphoblastic leukemia, but optimizing its dose is challenging due to large differences between patients in how the drug is metabolized and how they respond. This review discusses the pharmacometric models...