Moses L. Joloba

Analytical performance verification of the Deeplex Myc-TB assay using well-characterized Mycobacterium tuberculosis proficiency testing isolates

Rapid and accurate detection of drug-resistant Mycobacterium tuberculosis is critical for effective patient management and tuberculosis (TB) control. Targeted next-generation sequencing (tNGS) assays such as Deeplex® Myc-TB offer rapid detection of resistance-associated mutations...

Integrated in silico assessment of the regulatory and structural consequences of pulmonary tuberculosis-associated SP110 polymorphisms

Abstract The molecular mechanisms underlying conflicting findings of association of SP110 single nucleotide polymorphisms (SNPs) with susceptibility to pulmonary tuberculosis (PTB) remain unclear. We selected ten SP110 SNPs from publicly available genomic databases, based on prio...