Mosayeb Rostamian

Venom-derived and natural analgesic peptides: From venomics-based discovery to computational design and therapeutic development

Pain is a complex physiological process and an important clinical issue due to thelimitations of the existing analgesics. Side effects, tolerance anddependence, and limited efficacy for the treatment of chronic pain are common complications of classic drugs, e.g., opioids and non...

Clinical development of human vaccine candidates against Shigella flexneri: a systematic review of clinical trials

Shigella flexneri remains a leading cause of shigellosis, particularly in low- and middle-income countries, where it contributes substantially to childhood morbidity, mortality, and the growing burden of antimicrobial resistance. Despite decades of vaccine research, no licensed v...