Molly K. Burke

Age-specific genomic and transcriptomic variation reveals limited evidence for cis- regulatory interactions modulating aging in Saccharomyces cerevisiae

A bstract The budding yeast Saccharomyces cerevisiae is a well-established model for studying the genetic basis of complex traits, and it is a powerful system for investigating mechanisms of aging. Here, we examine the genomic and transcriptomic factors contributing to increased...

Dissecting fluctuating selection: A unified population and quantitative genetics framework

Abstract One of the longstanding debates in evolutionary biology is the effect of fluctuating selection on genetic changes in populations. However, the extent to which these periodic forces influence organisms at both genomic and phenotypic levels remains unclear. Despite the com...