Mohammed Wassim Hammami

Optical Coherence Tomography in Ophthalmology: Physical Principles, Image Formation, Resolution and Clinical Applications

Optical coherence tomography (OCT) enables depth-resolved imaging of tissue microstructure by measuring low-coherence interferometric signals and reconstructing their depth-dependent reflectivity. This review provides a comprehensive examination of the physical principles governi...

Diagnosis of Iron Deficiency: A Condensed Diagnostic Reference to the ASH 2026 Guidelines

A condensed diagnostic reference summarizing the diagnostic recommendations of the American Society of Hematology (ASH) 2026 Guidelines for the Diagnosis of Iron Deficiency, published in September 2026. This document presents the guideline's population-specific serum ferritin thr...

Closing the Post-Emergency Department Gap After Self-Harm: Emergency Department-Initiated and Early Follow-Up Strategies for Suicide Prevention

This critical narrative review evaluates whether emergency department (ED)-initiated interventions and early post-discharge strategies can be linked into a coherent continuum of suicide prevention following a self-harm presentation. Self-harm is among the most common reasons for...

Closing the Post-Emergency Department Gap After Self-Harm: Emergency Department-Initiated and Early Follow-Up Strategies for Suicide Prevention

This critical narrative review evaluates whether emergency department (ED)-initiated interventions and early post-discharge strategies can be linked into a coherent continuum of suicide prevention following a self-harm presentation. Self-harm is among the most common reasons for...

From "Undruggable" to Actionable: RAS(ON) Inhibition and the Emerging Therapeutic Landscape of Pancreatic Cancer

Activating mutations in RAS genes, overwhelmingly KRAS at codon 12, occur in more than 90% of pancreatic ductal adenocarcinomas (PDAC), yet for four decades RAS stood as the emblem of undruggability. This Perspective traces the reasoning that carried the field from failed indirec...

Mathematical, Physical, and Computational Principles of Rotational Thromboelastometry

Rotational thromboelastometry (ROTEM) is a viscoelastic assay used to evaluate whole blood coagulation dynamics in clinical settings. Despite its utility, commercial ROTEM analyzers operate as proprietary systems, obscuring the mechanical and computational algorithms that transla...