Miriam L. O’Duill

Copper‐Catalyzed Arylation of Cyclic and Bridged Diamines for Drug Discovery

Cyclic diamines are a privileged scaffold in medicinal chemistry, widely used to modulate physicochemical properties and as linker units in bifunctional molecules such as Proteolysis Targeting Chimeras. Existing approaches for aryl functionalization of these motifs rely on S N Ar...