Mir Amir Hossein Hosseini

Physiologically based pharmacokinetic modelling of levofloxacin as a tool for paediatric dose optimization

Aims Levofloxacin (LFX) is critical for paediatric community‐acquired pneumonia (CAP) and multidrug‐resistant tuberculosis (MDR‐TB). Current guideline doses may provide suboptimal exposure in younger children. This study aims to develop a paediatric physiologically based pharmaco...