Mingzhong Zhao

The two-component system CrdRS mediates sub-inhibitory antibiotic-induced biofilm formation in Helicobacter pylori via bidirectional regulation of transporters PlpA and GlnP

ABSTRACT Biofilm formation by Helicobacter pylori is a major driver of antibiotic tolerance and treatment failure, yet the signaling pathways that trigger biofilm development under sub-inhibitory antibiotic pressure remain poorly understood. Here, we show that sub-MIC levels of m...