Mingzheng Jiang

B3GNT3 defines a spatially restricted dysfunctional T-cell niche and predicts immunotherapeutic outcomes in lung adenocarcinoma

Abstract Background Immunotherapy response in lung adenocarcinoma (LUAD) remains highly heterogeneous, underscoring the need for biologically informative markers of tumor immune dysregulation. B3GNT3, a glycosyltransferase implicated in several malignancies, is poorly characteriz...