Mingyuan Gao

Active LysosomalNanoplatform for Ferroptosis-EnhancedImmunotherapy via Tumor Extracellular Matrix Remodeling

Abstract The therapeutic efficacy of nanomedicines in solid tumors is often limited by rapid systemic clearance, dense extracellular matrix (ECM) barriers, poor tumor cell selectivity, and an immunosuppressive tumor microenvironment. Herein, we report an active lysosome-encapsula...