Mingming Ding

Conformational entropy bottleneck in polymer nanopore interception driven by branching architecture and excluded volume

Abstract The transport of polymers through nanopores is fundamentally governed by the interplay between molecular topology and nanoconfinement. However, how branching architecture influences the critical interception size ( R h,c ) under weak compression—where diffusion dominates...

Low Dasatinib Penetration of the Blood–Brain Barrier in Children With Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia: Evidence From LC‐MS/MS Analysis

ABSTRACT We measured dasatinib concentrations in paired plasma and cerebrospinal fluid (CSF) samples from children with Philadelphia chromosome–positive acute lymphoblastic leukemia (Ph+ ALL). Blood samples were collected from children at 0 h (pre‐dasatinib) and 2 h post‐dasatini...