Mingkai Yang

Umpolung at the meta ‐Positions of Oxazino‐Pyridines Enabling Nucleophilic Pyridine Functionalization

ABSTRACT Selective C─H functionalization of azines is of paramount importance to synthetic and medicinal chemistry. However, nucleophilic functionalization at meta‐ position of pyridines has remained elusive because of the intrinsic polarity mismatch. In this study, we report a m...

Umpolung at the meta ‐Positions of Oxazino‐Pyridines Enabling Nucleophilic Pyridine Functionalization

Selective C─H functionalization of azines is of paramount importance to synthetic and medicinal chemistry. However, nucleophilic functionalization at meta-position of pyridines has remained elusive because of the intrinsic polarity mismatch. In this study, we report a mild and pr...