Minakshi Behera

34 Therapeutic Targeting of the SLC7A11-GCLM-GPX4 Axis Sensitizes Glioblastoma to Ferroptosis and Associates with Poor Survival

Abstract Background Glioblastoma (GBM) is the most common malignant primary brain tumor with a dismal prognosis. The high proliferative activity of GBM is prone to generating oxidative stress, which must be counteracted to support cell survival and prevent ferroptotic cell death....