Miles W. Carroll

Spike antibody Fc is associated with protection from SARS-CoV-2 challenge in macaques

A definitive correlate of protection (CoP) for SARS-CoV-2 has yet to be formally established. We previously reported that neutralising antibodies (NAbs) are the strongest candidate CoP for clinical protection against COVID-19 and that spike binding antibody is the strongest candi...

Early insights into predicted efficacy of Ebola monoclonal antibodies for the 2026 Bundibugyo virus disease outbreak

The 2026 Bundibugyo virus disease (BVD) outbreak in the DRC and Uganda raises urgent questions about the efficacy of existing Ebola virus (EBOV) monoclonal antibodies (mAbs) against Bundibugyo virus (BDBV). Here, we perform genomic and structural analyses of 44 BDBV sequences, in...