Mihaly Mezei

Ligand-Induced Stability Studies at the TSH Receptor Show the Linking Region to be a Chameleon

Glycoprotein hormone receptors (GPHRs) share a conserved architecture but the thyroid-stimulating hormone receptor (TSHR) is unique in possessing a large 141-amino-acid region called the hinge or linking region (LR) that contains a 50-amino-acid post translational cleavage site....