Michel Koole

Effects of motion and white matter hyperintensities on reference region based ¹⁸F-SynVesT-1 PET quantification in Alzheimer’s disease and healthy volunteers

18 F-SynVesT-1 is a PET tracer targeting synaptic vesicle protein 2A, a surrogate marker of synaptic density. Simplified quantification using pseudo-reference regions such as the centrum semiovale (CSO) or whole cerebellum (CER) has previously been validated in healthy volunteers...