Michael Thomas Marty

Evaluating a Lightweight Neural Network for Aggregate Isotope Distribution Prediction

Abstract Isotope distribution prediction is an important part of mass spectrometry data analysis. A variety of strategies have been developed, including brute-force polynomial methods and Fourier-transform (FT) convolution methods. Here, we present a novel neural network (NN) app...

Design of Fluorescent Membrane Scaffold Proteins for Nanodiscs

Abstract Nanodiscs are nanoscale lipid bilayer membrane mimetics surrounded by two membrane scaffold proteins (MSPs). They are widely used as soluble cassettes for membrane proteins and lipids in diverse applications in structural, functional, and biophysical studies. The origina...