Michael T. Kleinman

Exposure to airborne fine particulate matter disrupts human embryonic stem cell osteogenic differentiation

Developmental bone toxicity encompasses impairments in skeletal growth and remodeling during embryonic and fetal development that can result in long-term skeletal abnormalities. Airborne fine particulate matter (FPM; ≤ 2.5 μm) is a size-defined fraction of particulate air polluti...

Cigarette Smoke and E-Cigarette Aerosol Extracts Induce Myelopoiesis and Suppress Inflammatory Cytokine Production

Tobacco and nicotine use remain leading preventable drivers of cancer risk, and both combustible cigarettes and electronic nicotine devices perturb immune function and hematopoiesis. However, side-by-side comparisons of their effects across the hematopoietic hierarchy remain limi...