Michael S. Neuberger

Assessment of the effectiveness of protein in critical illness: the role of statistical shortcomings in explaining discrepancies between observational studies and randomized controlled trials

Until 2023, recommendations for prescribing protein to critically ill patients were largely based on observational studies and non-randomized interventions. Several large, multicentre non-randomized studies of intervention conducted between 2009 and 2017 consistently reported tha...