Michael R. Irwin

Menstrual cycle-related neurotrophic and inflammatory variation differs between adult females with and without Major Depressive Disorder

Abstract Background The pathophysiology of Major Depressive Disorder (MDD), which disproportionately affects females, has been linked to neuroimmune mechanisms. However, many canonical biomarkers of MDD may be influenced by physiological changes across the menstrual cycle. Despit...