Michael Maes

Cortical hemodynamic dysregulation is linked to peripheral NIMETOX pathways in major depressive disorder: an 89-channel fNIRS systems-biology study.

Background: Major depressive disorder (MDD) is clinically heterogeneous, but relationships among cortical hemodynamic abnormalities, peripheral neuroimmune, metabolic, and oxidative stress (NIMETOX) processes, and clinical phenome features remain unclear. We applied a systems-bio...

Transdiagnostic metabolic architecture across major depressive disorder and schizophrenia: a NIMETOX systems-biology approach

Background: Major depressive disorder (MDD) is conceptualised within a neuroimmune metabolic oxidative (NIMETOX) framework. From a systems-biology perspective, related metabolic oxidative disturbances may extend across diagnostic boundaries, including schizophrenia (SCZ), but the...