Michael J. Jurynec

Identificationand Validation of a Novel WNK2 Inhibitor:A New Genetically Informed Target for Osteoarthritis Drug Development

Abstract Osteoarthritis (OA) is a disease characterized by loss of joint space, degeneration of cartilage at articular surfaces, remodeling of bone and other joint tissues, low-grade inflammation, and pain. It is a leading cause of disability in the aging population. We do not ha...