Michael Hindle

Transnasal Administration of Surfactant Aerosol to the Lungs of Infants Using Direct Interfaces – Lessons Learned from Computational Fluid Dynamics

PURPOSE: Direct-to-infant (D2I) transnasal aerosol surfactant therapy (AST) offers a promising non-invasive alternative for treating neonatal respiratory distress syndrome (RDS). However, achieving high lung delivery efficiency with dry powder inhalers (DPIs) requires careful opt...