Michael E. Mullins

Comparison of propofol, diazepam, and pyridoxine for isoniazid-induced seizures in Swiss albino mice

Introduction Acute isoniazid toxicity causes refractory seizures due to pyridoxine deficiency-mediated gamma-aminobutyric acid depletion. While pyridoxine is the established antidote, its limited availability in emergency settings necessitates alternative treatments. Propofol is...