Michael Akcan

Increased Energy Expenditure through Intermittent Cold Exposure Does Not Enhance Tirzepatide Induced Weight-loss in Obese Mice

Obesity results from an imbalance between energy intake and energy expenditure. While pharmacological approaches such as tirzepatide, a dual GIP/GLP-1 receptor agonist, reduce food intake and body weight, enhancing energy expenditure via intermittent cold exposure–induced activat...