Michael A. Hoyt

Salivary Digital PCR With Epigenetic Cell Counting Correction as a Feasible Non-Invasive Platform for Longitudinal JAK2V617F Monitoring in Myeloproliferative Neoplasms

Abstract Intensive longitudinal monitoring of somatic mutation variant allele frequency (VAF) is needed to characterize clonal dynamics during therapy in myeloproliferative neoplasms (MPN). Salivary digital PCR, corrected for buccal epithelial DNA contamination by epigenetic cell...