Mi Hyun Lee

Stiffness-Dependent Mechanotransductive Signaling in Silicone Implant-Associated Fibrotic Encapsulation

Abstract Fibrotic encapsulation remains a major limitation of silicone-based soft-tissue implants and contributes to capsular contracture. Although biochemical and immunological factors have been extensively investigated, the contribution of implant stiffness to the peri-implant...