Mengyao Wu

AI LEGO: Scaffolding Cross-Functional Collaboration in Industrial Responsible AI Practices during Early Design Stages

Responsible AI (RAI) efforts increasingly emphasize the importance of addressing potential harms early in the AI development lifecycle through social-technical lenses. However, in cross-functional industry teams, this work is often stalled by a persistent coordination challenge:...

Active LysosomalNanoplatform for Ferroptosis-EnhancedImmunotherapy via Tumor Extracellular Matrix Remodeling

Abstract The therapeutic efficacy of nanomedicines in solid tumors is often limited by rapid systemic clearance, dense extracellular matrix (ECM) barriers, poor tumor cell selectivity, and an immunosuppressive tumor microenvironment. Herein, we report an active lysosome-encapsula...

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

ABSTRACT Ferroptosis contributes to Parkinson's disease (PD) through interconnected processes including iron dysregulation, oxidative stress, and mitochondrial dysfunction, yet current therapies targeting single pathways remain insufficient. Herein, we developed gallium–quercetin...