Mengting Shen

SUGP1 Deficiency Leads to Splicing Dysregulation and Reduced piRNA Abundance in Insects

SUGP1 (SURP and G-patch domain containing 1) participates in splice-site recognition through its interaction with SF3B1, and loss of this factor leads to aberrant splicing. While its role in pre-mRNA splicing is well-documented, its impact on small RNA pathways remains poorly und...