Author
Mehdi Cloarec
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Recent research
- BiologyOpen access
Pharmacological inhibition of UBASH3B induces mitotic arrest and selectively reduces tumor growth
Abstract Cancer cells tolerate mitotic errors to sustain proliferation, yet the molecular dependencies enabling this tolerance remain poorly understood and largely unexploited therapeutically. UBASH3B ensures mitotic fidelity by regulating Aurora B localization and is overexpress...