Mediterranean Journal of Medical Research

GC-MS analysis, in silico studies, and haematological activity of the bioactive profile of Sorghum bicolor leaf sheath in rats

Sorghum bicolor, locally called ‘Dawa’ (Hausa) and ‘Oka-pupa’ (Yoruba), is a widely cultivated cereal crop, mostly in northern Africa and other tropical regions. Beyond being a staple cereal, the sheath leaves have long been used in traditional medicine as a natural blood booster...

GC-MS analysis, in silico studies, and haematological activity of the bioactive profile of Sorghum bicolor leaf sheath in rats

Sorghum bicolor, locally called ‘Dawa’ (Hausa) and ‘Oka-pupa’ (Yoruba), is a widely cultivated cereal crop, mostly in northern Africa and other tropical regions. Beyond being a staple cereal, the sheath leaves have long been used in traditional medicine as a natural blood booster...

Carica papaya leaf suppresses platelet activation via inhibition of NADPH oxidase activity, calcium mobilization, and modulation of cAMP signaling

Platelet activation and thrombus propagation are driven in part by reactive oxygen species generated by NADPH oxidase, together with cytoplasmic calcium (Ca2+) mobilization and cyclic adenosine monophosphate (cAMP) signaling. Natural-product extracts with antiplatelet activity ar...

Hypoglycemia experience and pharmacist counseling among Libyan patients with diabetics mellites: a cross-sectional study

Hypoglycemia is an important treatment-related complication of diabetes and requires prompt recognition and appropriate self-management. Evidence from Libya on patients' hypoglycemia experience and the counseling they receive is limited. To describe self-reported hypoglycemia exp...

Hypoglycemia experience and pharmacist counseling among Libyan patients with diabetics mellites: a cross-sectional study

Hypoglycemia is an important treatment-related complication of diabetes and requires prompt recognition and appropriate self-management. Evidence from Libya on patients' hypoglycemia experience and the counseling they receive is limited. To describe self-reported hypoglycemia exp...

Kisspeptin signalling in male reproduction: Molecular mechanisms, biomarker potential, and therapeutic opportunities

Abstract: Kisspeptin, a peptide encoded by the KISS1 gene, has emerged as a principal regulator of the hypothalamic-pituitary-gonadal axis and plays a fundamental role in male reproductive physiology. Beyond its established function in stimulating gonadotropin-releasing hormone s...

Kisspeptin signalling in male reproduction: Molecular mechanisms, biomarker potential, and therapeutic opportunities

Abstract: Kisspeptin, a peptide encoded by the KISS1 gene, has emerged as a principal regulator of the hypothalamic-pituitary-gonadal axis and plays a fundamental role in male reproductive physiology. Beyond its established function in stimulating gonadotropin-releasing hormone s...