Mazin Aboobaida Abdalla Abdelaziz

Computational identification of isoflavonoids as novel PPAR-γ agonists for the treatment of type 2 diabetes mellitus

Background The management of type 2 diabetes mellitus (T2DM) using peroxisome proliferator-activated receptor gamma (PPAR-γ) agonists is currently limited by the adverse effects of thiazolidinediones (TZDs), such as fluid retention and weight gain. This necessitates the search fo...