Maximilian Bellut

NLRP3 Marks an Inflammatory Neutrophil–NETosis–Pyroptosis Network in Human Ischemic Stroke Thrombi

Background: Human ischemic stroke thrombi are increasingly recognized as biologically active immunothrombotic structures. While the NLRP3 inflammasome contributes to experimental stroke pathology, its role within human cerebral thrombi remains poorly understood. Methods: Thrombi...

Association of Enlarged Perivascular Spaces and Total Small Vessel Disease Burden With Kidney Function.

Background And Objectives Enlarged perivascular spaces (EPVSs) in the basal ganglia (BG-EPVS) are an important marker of cerebral small vessel disease (cSVD), and EPVS in the centrum semiovale (CSO-EPVS) are part of the diagnostic criteria for cerebral amyloid angiopathy. We aime...