Mauri A. Kostiainen

G-quadruplex aptamer conjugate for the enhanced recognition and eradication of Staphylococcus aureus biofilms

Abstract Bacterial biofilm-associated infections remain a major challenge in clinical settings. Innovative solutions are therefore urgently needed to improve the efficacy of antibacterial agents and to overcome biofilm tolerance. In this study, we sought to enhance the selectivit...

Effect of Electrolyte,Applied Voltage, and DNA Concentrationon the Translocation Dynamics of a Single-Stranded DNA through a Solid-StateNanopore

Abstract Solid-state nanopores enable label-free detection of biomolecules by monitoring ionic current modulations during molecular translocation. However, reliable measurements are often limited by rapid, poorly controlled translocation dynamics producing short, low-resolution s...