Matthias D. Koch

Type IV pilus length determines virulence by regulating a putative subpopulation of non-contributing filaments in Pseudomonas aeruginosa

Many clinically important bacterial pathogens, including Pseudomonas, Vibrio, Neisseria, and Acinetobacter species, employ dynamic extracellular appendages called type IV pili (T4P) to facilitate virulence through cyclical extension and retraction of pilus filaments. To dissect h...