Matthew H. Hotopf

Genetic evidence for the psychosis continuum: polygenic score analysis

Background The psychosis continuum conceptualises psychotic phenomena as existing on a spectrum from subclinical experiences to psychotic disorders. Despite epidemiological and clinical evidence in support of this model, few studies have examined polygenic liability across the se...

Investigating mechanisms and monitoring outcomes in functional neurological disorder: the unrealized potential of digital remote monitoring technologies

Functional neurological disorder (FND) is characterized by involuntary, distressing neurological symptoms that are distinguishable from other neurological diagnoses in presentation, aetiology and mechanisms. Significant disability, impaired quality-of-life and substantial healthc...