Matteo Luigi Giuseppe Leoni

Paracetamol: A History of Assumptions, Errors, and Evidence Reversals in Pain Management

Abstract Purpose of Review Paracetamol (acetaminophen) is among the most widely used medications in the history of humanity for treatment of pain conditions. For more than half a century, it has occupied a unique position as the archetypal first-line analgesic and antipyretic, re...

Microfragmented Adipose Tissue in Pain Management: Bridging Regenerative Biology and Clinical Therapeutics

Regenerative medicine has emerged as a transformative paradigm in contemporary healthcare, shifting the therapeutic focus from symptomatic management toward the restoration of tissue structure and function through biologically active interventions. Within this framework, adipose-...