Masato Matsuda

Functional Assessment of Platelet‐Derived Phospholipid Activity in Pooled Normal Plasmas by Low‐Phospholipid Thrombin Generation Assay and Its Impact on Lupus Anticoagulant Mixing Tests

ABSTRACT Background Pooled normal plasma (PNP) used for lupus anticoagulant (LA) mixing tests may carry platelet‐derived phospholipid (PL) activity introduced during freezing/lyophilization, potentially attenuating LA‐mediated prolongation of clotting times. Objectives To determi...

Machine learning enables clinically feasible implementation of clot waveform analysis for differentiating causes of prolonged activated partial thromboplastin time

Abstract Activated partial thromboplastin time (APTT) is widely used as a coagulation screening test; nonetheless, its prolongation can result from diverse causes, complicating the diagnosis. Clot waveform analysis (CWA) has been proposed as a complementary method, although the c...