Masakazu Hasegawa

PhenoDEL: A NovelScreening Strategy Based on IntracellularProtein Degradation Activity

Abstract Targeted protein degradation (TPD), including proteolysis targeting chimeras (PROTACs) and molecular glue degraders (MGDs), is a promising therapeutic approach. However, systematic discovery of such small molecules remains a major challenge. Here, we present PhenoDEL, a...